GATA-binding protein 3 enhances the utility of gross cystic disease fluid protein-15 and mammaglobin A in triple-negative breast cancer by immunohistochemistry.

@article{Huo2015GATAbindingP3,
  title={GATA-binding protein 3 enhances the utility of gross cystic disease fluid protein-15 and mammaglobin A in triple-negative breast cancer by immunohistochemistry.},
  author={Lei Huo and Yun Guo Gong and Ming Guo and Michael Z Gilcrease and Yun Wu and Hong Zhang and Jinxia Zhang and Erika Resetkova and Kelly K. Hunt and Michael T. Deavers},
  journal={Histopathology},
  year={2015},
  volume={67 2},
  pages={245-54}
}
AIMS We have demonstrated previously that gross cystic disease fluid protein-15 (GCDFP-15) and mammaglobin A (MAM) are of limited utility in triple-negative breast cancer (TNBC). GATA-binding protein 3 (GATA-3) is an emerging breast-associated immunohistochemical (IHC) marker with limited data in TNBC. Here, we examined GATA-3 expression in TNBC in comparison with GCDFP-15 and MAM. METHODS AND RESULTS We studied GATA-3, GCDFP-15 and MAM IHC expression in 62 primary and 68 metastatic TNBCs. In… CONTINUE READING
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