GAP junctional channel inhibition alters actin organization and calcium propagation in rat cultured astrocytes.

@article{Yamane2002GAPJC,
  title={GAP junctional channel inhibition alters actin organization and calcium propagation in rat cultured astrocytes.},
  author={Yoshihiro Yamane and Hatsuki Shiga and Hiroaki Asou and Etsuro Ito},
  journal={Neuroscience},
  year={2002},
  volume={112 3},
  pages={593-603}
}
Astrocytes are connected by gap junctions, which provide intercellular pathways that allow a direct exchange of ions and small metabolites including second messengers and the propagation of electric currents. The roles of gap junctional communication on whole-cell morphology, cytoskeletal organization, and intercellular communication in astrocytes are not yet clear even in vitro, though there are many studies that have examined the active relation between gap junctions and actin filaments in… CONTINUE READING

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