GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5

@article{Kwakowsky2007GADIE,
  title={GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5},
  author={A. Kwakowsky and M. Schwirtlich and Q. Zhang and D. Eisenstat and F. Erd{\'e}lyi and M. Baranyi and Z. Katarova and G. Szab{\'o}},
  journal={Developmental Dynamics},
  year={2007},
  volume={236}
}
Gamma‐aminobutyric acid (GABA), the major inhibitory neurotransmitter of the adult nervous system and its biosynthetic enzyme glutamic acid decarboxylase (GAD) are abundantly expressed in the embryonic nervous system and are involved in the modulation of cell proliferation, migration, and differentiation. Here we describe for the first time the expression of GABA and embryonic and adult GAD isoforms in the developing mouse lens. We show that the GAD isoforms are sequentially induced with… Expand
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