GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.

@article{Choi2008GAC1AG,
  title={GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.},
  author={Yoon-E Choi and Jillian A Brown and Courtney B Williams and Lorena L Canales and Won-Bo Shim},
  journal={Mycologia},
  year={2008},
  volume={100 5},
  pages={701-9}
}
Fusarium verticillioides (teleomorph Gibberella moniliformis) is an ascomycete known to produce a variety of secondary metabolites, including fumonisins, fusaric acid and bikaverin. These metabolites are synthesized when the fungus is under stress, notably nutrient limitations. To date we have limited understanding of the complex regulatory process associated with fungal secondary metabolism. In this study we generated a collection of F. verticillioides mutants by using REMI (restriction enzyme… CONTINUE READING
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