GABAergic regulation of REM sleep in reticularis pontis oralis ( RPO ) and caudalis ( RPC ) in rats

@inproceedings{Sanford2003GABAergicRO,
  title={GABAergic regulation of REM sleep in reticularis pontis oralis ( RPO ) and caudalis ( RPC ) in rats},
  author={Larry D. Sanford and Xiangdong Tang and Jihua Xiao and Richard J. M. Ross and Adrian R. Morrison},
  year={2003}
}
The nucleus reticularis pontis oralis (RPO) and nucleus reticularis pontis caudalis (RPC) are implicated in the generation of rapid eye movement sleep (REM). Work in cats has indicated that GABA in RPO plays a role in the regulation of REM. We assessed REM after local microinjections into RPO and RPC of the GABAA agonist, muscimol (MUS), and the GABAA antagonist, bicuculline (BIC). Rats (90 day old male Sprague-Dawley) were implanted with electrodes for recording EEG and EMG. Guide cannulae… CONTINUE READING