GABAergic modulation of ventilatory response to acute and sustained hypoxia in obese Zucker rats

@article{Lin2005GABAergicMO,
  title={GABAergic modulation of ventilatory response to acute and sustained hypoxia in obese Zucker rats},
  author={Tao Lin and Ming Lo and Cong-xin Huang and Hua Ting and S -D Lee},
  journal={International Journal of Obesity},
  year={2005},
  volume={29},
  pages={188-195}
}
OBJECTIVE:To determine whether altered central and/or peripheral gamma-aminobutyric acid (GABA)ergic mechanisms acting in GABAA receptors contribute to the abnormal ventilatory response to acute and sustained hypoxia in obese Zucker rats.METHODS:In all, 10 lean and 10 obese Zucker rats were studied at 12 weeks of age. Ventilation ([Vdot ]E), tidal volume (VT), and breathing frequency (f) during room air breathing and in response to sustained (30 min) hypoxic (10% O2) challenges were measured on… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Similar Papers

Loading similar papers…