• Corpus ID: 82236524

GABAergic mechanisms in the mammalian periphery

  title={GABAergic mechanisms in the mammalian periphery},
  author={S{\'a}ndor L. Erdő and N. G. Bowery},
GABA in the Mammalian Enteric Nervous System.
  • A. Krantis
  • Biology
    News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
  • 2000
Disruption in gastrointestinal function following perturbation of enteric GABA receptors presents potential new target sites for drug development.
GABA Outside the CNS
  • S. Erdő
  • Biology
    Springer Berlin Heidelberg
  • 1992
The GABAergic System in Human Female Genital Organs and Neurotransmitter Amino Acids as Modulators of Biological Processes of Spermatozoa are studied.
Occurrence of GABA and GABA receptors in human spermatozoa.
Low micromolar concentrations of the GABA(A) agonist, muscimol, were sufficient to significantly increase sperm hyperactivity, suggesting that the effect of GABA on human sperm motility might be mediated through a specific GABA( A) receptor.
Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract
Findings reveal the crucial role of the microbial GAD activity of L. lactis NCDO2118 to deliver GABA into the gastro-intestinal tract for exerting antinociceptive properties in vivo and open avenues for this GRAS (Generally Recognized As safe) bacterium in the management of visceral pain and anxious profile of IBS patients.
Journal of Reproduction and Development
This research supports the hypothesis that NT acts as a key modulator of fertilization and conception in cattle and proposes that NT selectively acts upon sperm via NTR1 and NTR2 during IVF to improve the cleavage rate and quality of blastocysts, which are important determinants of sperm quality for successful conception.
Capacitation of mouse sperm is modulated by gamma-aminobutyric acid (GABA) concentration
Results indicate that the GABA concentration can act as a modulator of the acrosome reaction and sperm capacitation in the female reproductive tract.
Neural mechanisms involved in enterotoxin- induced intestinal hypersecretion
Clostridium difficile toxin A and GABA increase the excitability of myenteric intrinsic sensory neurons in the guinea-pig jejunum through a GABAA receptor independent mechanism.
Protective roles of hepatic GABA signaling in acute liver injury of rats.
Treating rats with GABA or the GABAAR agonist muscimol, but not the GABABR agonist baclofen, protected hepatocytes against GalN toxicity and improved liver function, revealing that a complex GABA signaling system exists in the rat liver.
The role of GABAA in the expression of updated information through the reconsolidation process in humans
A Brief History of the GABA B Receptor
This work examined the influence of GABA and its analogues on the evoked release of radiolabelled noradrenaline from sympathetic nerve fibres innervating rat isolated atria and designated this novel receptor ‘GABAB’ to contrast with the classical ‘GABAA’ site.