GABAergic mRNA expression is upregulated in the prefrontal cortex of rats sensitized to methamphetamine.

Abstract

Inhibitory gamma-aminobutyric acid (GABA)-mediated neurotransmission plays an important role in the regulation of the prefrontal cortex (PFC), with increasing evidence suggesting that dysfunctional GABAergic processing of the PFC may underlie certain deficits reported across psychotic disorders. Methamphetamine (METH) is a psychostimulant that induces… (More)
DOI: 10.1016/j.bbr.2015.10.026

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