GABAergic and glycinergic synapses onto neurokinin-1 receptor-immunoreactive neurons in the pre-Bötzinger complex of rats: light and electron microscopic studies.

@article{Liu2002GABAergicAG,
  title={GABAergic and glycinergic synapses onto neurokinin-1 receptor-immunoreactive neurons in the pre-B{\"o}tzinger complex of rats: light and electron microscopic studies.},
  author={Ying-ying Liu and Margaret T. T. Wong-Riley and Jin-Ping Liu and Yi Tao Jia and Hui-ling Liu and Xi-ying Jiao and Gong Ju},
  journal={The European journal of neuroscience},
  year={2002},
  volume={16 6},
  pages={1058-66}
}
The pre-Bötzinger complex (preBötC) in the ventrolateral medulla is thought to be the kernel for respiratory rhythm generation. Neurons in the preBötC contain intense neurokinin-1 receptor (NK1R) immunoreactivity. Some of these neurons in the adult preBötC are presumed to be the pre-inspiratory interneurons that are essential for generating respiratory rhythm in the neonate. Chloride-mediated synaptic inhibition is critical for rhythmogenesis in the adult. The present study used… CONTINUE READING

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