GABAergic and asymmetrical synapses on somata of GABAergic neurons in CA1 and CA3 regions of rat hippocampus. A quantitative electron microscopic analysis.

@article{Yao1996GABAergicAA,
  title={GABAergic and asymmetrical synapses on somata of GABAergic neurons in CA1 and CA3 regions of rat hippocampus. A quantitative electron microscopic analysis.},
  author={Zhongbing Yao and Xiaohui Li and Zao Cheng Xu},
  journal={Stroke},
  year={1996},
  volume={27 8},
  pages={
          1411-5; discussion 1415-6
        }
}
BACKGROUND AND PURPOSE CA1 pyramidal neurons in hippocampus die while CA3 neurons survive after transient ischemia. The imbalance of excitation and inhibition may contribute to this selective vulnerability. The purpose of this study was to examine the morphological basis of the above hypothesis. METHODS Male Wistar rats were perfused with 4% parafor-maldehyde and 0.2% glutaraldehyde in 0.15 mol/L phosphate buffer. Coronal sections (50 microns) cut on a microtome were processed for gamma… CONTINUE READING