GABAergic analgesia: new insights from mutant mice and subtype-selective agonists.

@article{Zeilhofer2009GABAergicAN,
  title={GABAergic analgesia: new insights from mutant mice and subtype-selective agonists.},
  author={Hanns Ulrich Zeilhofer and Hanns M{\"o}hler and Alessandra Di Lio},
  journal={Trends in pharmacological sciences},
  year={2009},
  volume={30 8},
  pages={397-402}
}
Gamma-aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the brain where it regulates many physiological functions including sleep, anxiety, reward and memory formation. GABAergic neurons and ionotropic GABA(A) receptors are also found in the spinal cord dorsal horn where they control the propagation of pain signals from the… CONTINUE READING