GABAergic Neurons in Mammalian Thalamus: A Marker of Thalamic Complexity?

  title={GABAergic Neurons in Mammalian Thalamus: A Marker of Thalamic Complexity?},
  author={Paola Arcelli and Carolina Frassoni and Maria Cristina Regondi and Silvia de Biasi and Roberto Spreafico},
  journal={Brain Research Bulletin},

Parvalbumin and GABA in the developing somatosensory thalamus of the rat: an immunocytochemical ultrastructural correlation

The results demonstrate the late expression of PV and acquisition of adult morphology in ascending terminals of rat VB during postnatal development in comparison with the innervation arising from the GABAergic RT.

Comparison of numbers of interneurons in three thalamic nuclei of normal and epileptic rats

Findings show that in the VPL and the VPM there are relatively more GABAergic interneurons in GAERS than in Wistar rats, which may represent a compensatory response of the thalamocortical circuitry to the absence seizures or may be related to the production of absence seizures.

GABA signaling in the thalamus

The results arising from the present thesis challenge the view that the diversity of GABAergic signaling in thalamus is comparatively limited and proposes that, to fully understand GABAergic signaled, at least two additional aspects have to be considered.

Inhibitory interneurons distribute widely across the mouse thalamus and form ontogenetic spatial clusters

A larger than expected complexity and distribution of interneurons across the mouse thalamus is identified, and markers for the midbrain-born class are abundantly expressed in the primate Thalamus, pointing to a shared ontogenetic organization of thalamic interneuronons across mammals.

Postnatal Development of GABAergic Synapses in the Nigral and Entopeduncular Afferent Territory of the Rat Thalamus

The time course of the development of GABAergic synapses in the basal ganglion afferent territories of the rat thalamus was analyzed, implying that anatomical and connectional differences between thalamic nuclei are also reflected in the patterns of their synaptogenesis.

Dual midbrain and forebrain origins of thalamic inhibitory interneurons

It is observed that markers for the midbrain-born class are abundantly expressed throughout the thalamus of the New World monkey marmoset, revealing that the blueprint of the ontogenetic organisation of thalamic interneurons of larger-brained mammals exists and can be studied in mice.



Morphology of neurons in the thalamic reticular nucleus (TRN) of mammals as revealed by intracellular injections into fixed brain slices

  • J. Lübke
  • Biology
    The Journal of comparative neurology
  • 1993
No obvious basis for classification of neurons in the mammalian TRN according to dendritic morphology is found and there seems to be no difference in neuronal morphology of TRN neurons in relation to different intrinsic thalamic organisation within or between species.

A description of the GABAergic neurons and axon terminals in the motor nuclei of the cat thalamus

The GABA neurons and their processes in the cat motor thalamic nuclei were identified and studied with glutamic acid decarboxylase (GAD) immunocytochemistry at both the light and electron microscopic

The reticular thalamic nucleus (RTN) of the rat: Cytoarchitectural, Golgi, immunocytochemical, and horseradish peroxidase study

By means of the horseradish peroxidase and the immunocytochemical study, it has been confirmed that all three groups of neurons project within the thalamus and that they are GABAergic.

Fine structure of the ventral lateral nucleus (VL) of the Macaca mulatta thalamus: Cell types and synaptology

Ultrastructure of the major cerebellar territory of the monkey thalamus, or VL, was analyzed by using neuroanatomical tracing, immunocytochemical, and quantitative morphometric techniques and can be further distinguished by ultrastructural features.

Ultrastructural analysis of gaba‐immunoreactive elements in the monkey thalamic ventrobasal complex

The majority of synaptic contacts between pleomorphic vesicle‐containing profiles appear to be between PSD‐boutons and other components of interneurons, suggesting the principal GABAergic input to interneuronons in the primate ventrobasal complex is derived from other interneURons.