GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders

@inproceedings{ElAnsary2014GABAergicglutamatergicIR,
  title={GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders},
  author={Afaf El-Ansary and Laila Al-Ayadhi},
  booktitle={Journal of Neuroinflammation},
  year={2014}
}
Autism spectrum disorder (ASD) is characterized by three core behavioral domains: social deficits, impaired communication, and repetitive behaviors. Glutamatergic/GABAergic imbalance has been found in various preclinical models of ASD. Additionally, autoimmunity immune dysfunction, and neuroinflammation are also considered as etiological mechanisms of this disorder. This study aimed to elucidate the relationship between glutamatergic/ GABAergic imbalance and neuroinflammation as two recently… CONTINUE READING

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