GABAB receptors presynaptically modulate excitatory synaptic transmission in the rat supraoptic nucleus in vitro.

@article{Kombian1996GABABRP,
  title={GABAB receptors presynaptically modulate excitatory synaptic transmission in the rat supraoptic nucleus in vitro.},
  author={Samuel B. Kombian and Jeffrey A Zidichouski and Quentin J Pittman},
  journal={Journal of neurophysiology},
  year={1996},
  volume={76 2},
  pages={1166-79}
}
1. The effect of gamma-aminobutyric acid-B (GABAB)-receptor activation on excitatory synaptic transmission in the rat supraoptic nucleus (SON) was examined using the nystatin perforated-patch whole cell recording technique in coronal hypothalamic slices. 2. Stimulation of the hypothalamic region dorso-medial to the SON elicited glutamate and GABAA-receptor-mediated synaptic responses in electrophysiologically identified magnocellular neurosecretory cells. 3. Bath application of the GABAB… CONTINUE READING