GABAB-receptor-mediated inhibition reduces the orientation selectivity of the sustained response of striate cortical neurons in cats.

@article{Allison1996GABABreceptormediatedIR,
  title={GABAB-receptor-mediated inhibition reduces the orientation selectivity of the sustained response of striate cortical neurons in cats.},
  author={John D. Allison and Jon Kabara and R. K. Snider and Vivien A. Casagrande and A. B. Bonds},
  journal={Visual neuroscience},
  year={1996},
  volume={13 3},
  pages={559-66}
}
Blocking GABAA-receptor-mediated inhibition reduces the selectivity of striate cortical neurons for the orientation of a light bar primarily by reducing the selectivity of their onset transient (initial 200 ms) response. Blocking GABAB-receptor-mediated inhibition with phaclofen, however, is not reported to reduce the orientation selectivity of these neurons when it is measured with a light bar. We hypothesized that blocking GABAB-receptor-mediated inhibition would instead affect the… CONTINUE READING

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