GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra.

@article{Engberg1993GABABreceptorAA,
  title={GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra.},
  author={G{\"o}ran Engberg and T. Kling-Petersen and Hans Nissbrandt},
  journal={Synapse},
  year={1993},
  volume={15 3},
  pages={229-38}
}
Previous electrophysiological experiments have emphasized the importance of the firing pattern for the functioning of midbrain dopamine (DA) neurons. In this regard, excitatory amino acid receptors appear to constitute an important modulatory control mechanism. In the present study, extracellular recording techniques were used to investigate the significance of GABAB-receptor activation for the firing properties of DA neurons in the substantia nigra (SN) in the rat. Intravenous administration… CONTINUE READING