GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons.

@article{Sodickson1996GABABRI,
  title={GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons.},
  author={D L Sodickson and Bruce P. Bean},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1996},
  volume={16 20},
  pages={6374-85}
}
GABA and the GABAB receptor agonist baclofen activated a potassium conductance in acutely dissociated hippocampal CA3 neurons. Baclofen-activated current required internal GTP, was purely potassium selective, and showed strong inward rectification. As with acetylcholine-activated current in atrial myocytes, external Cs+ blocked inward but not outward current in a highly voltage-dependent manner, whereas Ba2+ blocked with no voltage dependence. Unlike the cardiac current, however, the baclofen… CONTINUE READING
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GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures.

Proceedings of the National Academy of Sciences of the United States of America • 1985
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