• DOI:10.1007/BF00805843
Corpus ID: 2891788

GABAA receptors on rat cerebellar granule cells are potently activated by muscimol but only slightly modulated by the benzodiazepine agonist flunitrazepam

@article{Baldelli2004GABAARO,
  title={GABAA receptors on rat cerebellar granule cells are potently activated by muscimol but only slightly modulated by the benzodiazepine agonist flunitrazepam},
  author={P. Baldelli and A. Cupello and M. Robello},
  journal={Amino Acids},
  year={2004},
  volume={6},
  pages={155-163}
}

P. Baldelli, A. Cupello, M. Robello

Published 2004

Biology, Medicine

Amino Acids

SummaryGABAA receptors present on rat cerebellar granule cells in culture were studied by the whole cell patch clamp technique. Muscimol appeared to be more potent than GABA itself in activating Cl− currents. A benzodiazepine, flunitrazepam, only slightly (10%) potentiated the GABA action.These results support the previous suggestion that GABAA receptors containing theδ subunit, such as those in the cerebellum granule cells, are potently activated by muscimol. The present results also bear out… CONTINUE READING

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