GABAA receptors in the ventral tegmental area control bidirectional reward signalling between dopaminergic and non‐dopaminergic neural motivational systems

@article{Laviolette2001GABAARI,
  title={GABAA receptors in the ventral tegmental area control bidirectional reward signalling between dopaminergic and non‐dopaminergic neural motivational systems},
  author={S. Laviolette and D. van der Kooy},
  journal={European Journal of Neuroscience},
  year={2001},
  volume={13}
}
In the midbrain ventral tegmental area (VTA), both dopaminergic and nondopaminergic neural substrates mediate various behavioural reward phenomena. VTA GABAergic neurons are anatomically positioned to influence the activity of both the mesolimbic dopamine system and nondopamine efferents from the VTA. In order to examine the possible functional role of VTA GABAA receptors in neural reward processes, we performed discrete, bilateral microinjections of the GABAA receptor agonist, muscimol, or the… Expand
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