GABAA receptor polymorphisms in alcohol use disorder in the GWAS era

@article{Koulentaki2018GABAARP,
  title={GABAA receptor polymorphisms in alcohol use disorder in the GWAS era},
  author={Mairi Koulentaki and Elias Kouroumalis},
  journal={Psychopharmacology},
  year={2018},
  volume={235},
  pages={1845-1865}
}
Alcohol use disorder (AUD) is a chronic, relapsing, neuro-psychiatric illness of high prevalence and with a serious public health impact worldwide. It is complex and polygenic, with a heritability of about 50%, and influenced by environmental causal heterogeneity. Risk factors associated with its etiology have a genetic component. GABA (γ-aminobutyric acid) is a major inhibitory neurotransmitter in mammalian brain. GABAA receptors are believed to mediate some of the physiological and behavioral… 

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TLDR
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