GABAA receptor heterogeneity, function, and implications for epilepsy

  title={GABAA receptor heterogeneity, function, and implications for epilepsy},
  author={Eduardo E. Benarroch},
  pages={612 - 614}
  • E. Benarroch
  • Published 20 February 2007
  • Chemistry, Medicine
  • Neurology
Gamma-aminobutyric acid (GABA) is the neurotransmitter of the local inhibitory neurons that control neuronal excitability and network interactions in the cerebral cortex. Most of the cortical inhibitory effects of GABA are mediated by GABAA receptors. Cortical GABAergic mechanisms are important in epileptogenesis and provide a target of antiepileptic drug therapy. Over the past several years, there has been increasing understanding of the heterogeneous molecular structure, function, and… Expand
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