GABAA receptor channels.

@article{Macdonald1994GABAARC,
  title={GABAA receptor channels.},
  author={Robert L. Macdonald and Richard W. Olsen},
  journal={Annual review of neuroscience},
  year={1994},
  volume={17},
  pages={
          569-602
        }
}
This chapter discusses the gamma-aminobutyric acid (GABA) receptor channels, which are the most abundant inhibitory neurotransmitter in the CNS. Following release from presynaptic vesicles, GABA exerts fast inhibitory effects by interacting with GABA receptors, whose primary function is to hyperpolarize neuronal membranes in mature CNS neurons. GABA receptors are found both presynaptically, where they decrease the likelihood of neurotransmitter release, and postsynaptically, where they decrease… 
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TLDR
The isolation of a cloned cDNA encoding a new GABAA receptor subunit, termed γ2, which shares approximately 40% sequence identity with α-and β-subunits and whose messenger RNA is prominently localized in neuronal subpopulations throughout the CNS.
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Gamma aminobutyric acid mediates fast synaptic inhibition in the central nervous system by activating the chloride-permeable GABAA channel, and this "run down" of the GABA-activated conductance can be prevented by the inclusion of magnesium adenosine triphosphate and calcium buffer in the intracellular medium.
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TLDR
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