GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton

@article{Wang1999GABAAreceptorassociatedPL,
  title={GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton},
  author={Hongbing Wang and F. Bedford and N. Brandon and S. Moss and R. Olsen},
  journal={Nature},
  year={1999},
  volume={397},
  pages={69-72}
}
Type-A receptors for the neurotransmitter GABA (γ-aminobutyric acid) are ligand-gated chloride channels that mediate inhibitory neurotransmission. Each subunit of the pentameric receptor protein has ligand-binding sites in the amino-terminal extracellular domain and four membrane-spanning regions, one of which forms a wall of the ion channel. Each subunit also has a large intracellular loop that may be a target for protein kinases and be required for subcellular targeting and membrane… Expand
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