GABAA and GABAB receptors in the nucleus accumbens shell differentially modulate dopamine and acetylcholine receptor-mediated turning behaviour

@article{Akiyama2004GABAAAG,
  title={GABAA and GABAB receptors in the nucleus accumbens shell differentially modulate dopamine and acetylcholine receptor-mediated turning behaviour},
  author={Gaku Akiyama and Hiroko Ikeda and Satoshi Matsuzaki and Michiko Sato and Shoko Moribe and Noriaki Koshikawa and Alexander Rudolf Cools},
  journal={Neuropharmacology},
  year={2004},
  volume={46},
  pages={1082-1088}
}

GABA(A) receptors in the nucleus accumbens core modulate turning behavior induced by dopamine receptor stimulation.

It is concluded that neither GABA(A) nor GABA(B) receptor stimulation in the core of the nucleus accumbens produces turning behavior, and thatGAB(A), but not GABA( B), receptors in the nucleus Accumbens core may modulate dopamine D1-like/D2-like receptor-mediated pivoting.

Genetic and pharmacological investigation of α4-containing GABAA receptors in conditioned behaviours influenced by cocaine

The data presented within this thesis indicate that α4-GABAAR-mediated inhibition of D1- and D2-expressing neurons plays an important physiological role in controlling behavioural responses to conditioned cues and NAc α4βδ GABAARs may provide a potential therapeutic target by which to limit the enhancement of locomotor and conditioned-behaviours by cocaine.

N-Methyl-d-aspartate Modulation of Nucleus Accumbens Dopamine Release by Metabotropic Glutamate Receptors: Fast Cyclic Voltammetry Studies in Rat Brain Slices in Vitro.

The hypothesis that NMDA receptor activation modulates accumbens dopamine release is tested, and that phencyclidine pretreatment altered this modulation is supported, and the hypothesis that there is no enduring direct effect of PCP at NMDA receptors after this pretreatment procedure is supported.

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Contralateral turning elicited by unilateral stimulation of dopamine D2 and D1 receptors in the nucleus accumbens of rats is due to stimulation of these receptors in the shell, but not the core, of this nucleus

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