• DOI:10.1098/rspb.1988.0006
Corpus ID: 40290279

GABA receptors on the cell-body membrane of an identified insect motor neuron

@article{Sattelle1988GABARO,
  title={GABA receptors on the cell-body membrane of an identified insect motor neuron},
  author={D. Sattelle and R. Pinnock and K. Wafford and J. David},
  journal={Proceedings of the Royal Society of London. Series B. Biological Sciences},
  year={1988},
  volume={232},
  pages={443 - 456}
}

D. Sattelle, R. Pinnock, +1 author J. David

Published 1988

Biology, Medicine

Proceedings of the Royal Society of London. Series B. Biological Sciences

The pharmacology of a γ-aminobutyric acid (GABA) receptor on the cell body of an identified motor neuron of the cockroach (Periplaneta americana) was investigated by current-clamp and voltage-clamp methods. Iontophoretic application of GABA increased membrane conductance to chloride ions, and prolonged application resulted in desensitization. Hill coefficients, determined from dose–response data, indicated that binding of at least two GABA molecules was required to activate the chloride channel… CONTINUE READING

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