GABA receptors on the cell-body membrane of an identified insect motor neuron

@article{Sattelle1988GABARO,
  title={GABA receptors on the cell-body membrane of an identified insect motor neuron},
  author={David B. Sattelle and Robert D. Pinnock and Keith A. Wafford and Jonathan A. David},
  journal={Proceedings of the Royal Society of London. Series B. Biological Sciences},
  year={1988},
  volume={232},
  pages={443 - 456}
}
The pharmacology of a γ-aminobutyric acid (GABA) receptor on the cell body of an identified motor neuron of the cockroach (Periplaneta americana) was investigated by current-clamp and voltage-clamp methods. Iontophoretic application of GABA increased membrane conductance to chloride ions, and prolonged application resulted in desensitization. Hill coefficients, determined from dose–response data, indicated that binding of at least two GABA molecules was required to activate the chloride channel… 

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Ionic events following GABA receptor activation in an identified insect motor neuron
TLDR
The ionic events underlying γ-aminobutyric acid (GABA) receptor activation on the cell body of a cockroach identified motor neuron were investigated by using current-clamp and voltage-clamps techniques and confirmed that an influx of chloride ions mediated the GABA response.
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