GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats.

@article{Alam2005GABAmediatedCO,
  title={GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats.},
  author={Md Noor Alam and Sunil Kumar and Tariq Bashir and Natalia Suntsova and Melvi M Methippara and Ronald Szymusiak and Dennis McGinty},
  journal={The Journal of physiology},
  year={2005},
  volume={563 Pt 2},
  pages={569-82}
}
The perifornical-lateral hypothalamic area (PF-LHA) has been implicated in the regulation of behavioural arousal. The PF-LHA contains several cell types including neurones expressing the peptides, hypocretin (HCRT; also called orexin) and melanin-concentrating hormone (MCH). Evidence suggests that most of the PF-LHA neurones, including HCRT neurones, are active during waking and quiescent during non-rapid eye movement (non-NREM) sleep. The PF-LHA contains local GABAergic interneurones and also… CONTINUE READING

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