GABA-induced inactivation of functionally characterized sites in cat visual cortex (area 18): effects on orientation tuning.

@article{Crook1992GABAinducedIO,
  title={GABA-induced inactivation of functionally characterized sites in cat visual cortex (area 18): effects on orientation tuning.},
  author={John M. Crook and Ulf T. Eysel},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1992},
  volume={12 5},
  pages={1816-25}
}
Microiontophoresis of the inhibitory transmitter GABA was used to reversibly inactivate small sites of defined orientation specificity at a horizontal distance of some 600 microns from single cells recorded in area 18 of cat visual cortex, and the effects on orientation tuning were studied. The receptive fields of cells at the recording and inactivation sites overlapped extensively. During the inactivation of sites where the orientation preference differed by 45 degrees or more from that of a… CONTINUE READING