GABA and the GABAA receptor.

  title={GABA and the GABAA receptor.},
  author={S John Mihic and R. Adron Harris},
  journal={Alcohol health and research world},
  volume={21 2},
The neurotransmitter gamma-aminobutyric acid (GABA) inhibits the activity of signal-receiving neurons by interacting with the GABAA receptor on these cells. The GABAA receptor is a channel-forming protein that allows the passage of chloride ions into the cells. Excessive GABAA activation may play a role in mediating the sedative effects of alcohol and other sedating and anesthetic agents. For example, alcohol enhances the GABAA-mediated chloride flow into cells and may thereby enhance neuronal… CONTINUE READING
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