GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.

@article{Shreve1991GABAAG,
  title={GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.},
  author={Patti Shreve and Norman J. Uretsky},
  journal={Pharmacology, biochemistry, and behavior},
  year={1991},
  volume={38 2},
  pages={385-8}
}
Previous studies have shown that excitatory amino acid agonists or GABAergic antagonists injected into the substantia innominata/lateral preoptic area (SI/LPO) can produce the stimulation of coordinated locomotor activity. The purpose of the present study was to determine whether GABAergic and glutamatergic mechanisms in the SI/LPO interact to regulate locomotor activity. The stimulation of locomotor activity produced by the bilateral injection into the SI/LPO of 0.5 microgram of AMPA, a potent… CONTINUE READING
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