GABA and glutamate in children with Tourette syndrome: A 1H MR spectroscopy study at 7T.


Tourette syndrome (TS) is characterized by presence of chronic, fluctuating motor and phonic tics. The underlying neurobiological basis for these movements is hypothesized to involve cortical-striatal-thalamo-cortical (CSTC) pathways. Two major neurotransmitters within these circuits are γ-aminobutyric acid (GABA) and glutamate. Seventy-five participants… (More)
DOI: 10.1016/j.pscychresns.2017.12.005

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