GABA and benzodiazepine binding sites in spontaneously hypertensive rat.

The binding of GABA to its central receptor sites and of benzodiazepines to central and peripheral types of binding sites was compared in age-matched spontaneously hypertensive rat (SHR) and normotensive (WKY) rat. The KD and Bmax values of GABA agonist binding were not significantly different between SHR and WKY rat in the forebrain, cerebellum or pons… CONTINUE READING