GABA‐producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

@inproceedings{Pokusaeva2017GABAproducingB,
  title={
GABA‐producing Bifidobacterium dentium modulates visceral sensitivity in the intestine},
  author={Karina Pokusaeva and Cali E. Johnson and Berkley Luk and Giselle Uribe and Yu Fu and Numan Oezguen and Ris{\"e} K. Matsunami and M{\'o}nica Mart{\'i}nez Lugo and Aleksandar Major and Y. Mori‐Akiyama and Emily Brooke Hollister and Sara M. Dann and X Z Shi and David A. Engler and Tor C. Savidge and James Versalovic},
  booktitle={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society},
  year={2017}
}
BACKGROUND Recurrent abdominal pain is a common and costly health-care problem attributed, in part, to visceral hypersensitivity. Increasing evidence suggests that gut bacteria contribute to abdominal pain perception by modulating the microbiome-gut-brain axis. However, specific microbial signals remain poorly defined. γ-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter and a key regulator of abdominal and central pain perception from peripheral afferent neurons. Although gut… CONTINUE READING
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