GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations.

@article{BenAri2007GABAAP,
  title={GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations.},
  author={Yehezkel Ben-Ari and Jean-Luc Gaiarsa and Roman Tyzio and Rustem Khazipov},
  journal={Physiological reviews},
  year={2007},
  volume={87 4},
  pages={
          1215-84
        }
}
Developing networks follow common rules to shift from silent cells to coactive networks that operate via thousands of synapses. This review deals with some of these rules and in particular those concerning the crucial role of the neurotransmitter gamma-aminobuytric acid (GABA), which operates primarily via chloride-permeable GABA(A) receptor channels. In all developing animal species and brain structures investigated, neurons have a higher intracellular chloride concentration at an early stage… Expand
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