GABA(A) receptor heterogeneity in histaminergic neurons.

  title={GABA(A) receptor heterogeneity in histaminergic neurons.},
  author={Olga A. Sergeeva and Krister S. Eriksson and Irina N Sharonova and Vladimir S Vorobjev and Helmut L. Haas},
  journal={The European journal of neuroscience},
  volume={16 8},
Histaminergic neurons of the tuberomamillary nucleus display pacemaker properties; their firing rate is regulated according to behavioural state by gabaergic inhibition. Whole-cell recordings and single-cell RT-PCR from acutely isolated rat tuberomamillary neurons were used to characterize GABA -evoked currents and to correlate them with the expression pattern of 12 GABAA receptor subunits. We report differences in sensitivity to GABA and zinc as well as in the modulation of IPSC-decay times by… CONTINUE READING