GABA(A) receptor activity and PKC control inhibitory synaptogenesis in CNS tissue slices.

Abstract

The molecular signals inducing the formation of inhibitory synapses early in development have remained enigmatic. Here we focus on the role of PKC and GABA(A)R receptor activation in the formation of GABAergic synapses in a natural cellular environment. Rapid synaptogenesis was observed in horizontal slices from the superior colliculus of embryonic (E19… (More)

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