GABA(A) receptor activation at medullary sympathetic neurons contributes to postexercise hypotension.

@article{Kajekar2002GABAARA,
  title={GABA(A) receptor activation at medullary sympathetic neurons contributes to postexercise hypotension.},
  author={Radhika Kajekar and C Y Chen and Tatsushi Mutoh and Ann C. Bonham},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2002},
  volume={282 5},
  pages={H1615-24}
}
A single bout of exercise results in a postexercise hypotension (PEH) that is accompanied by a reduced baroreflex function. Based on the role of rostral ventrolateral medulla (RVLM) neurons in controlling sympathetic nerve activity (SNA) and blood pressure, the role of gamma-aminobutyric acid (GABA) in controlling RVLM neuronal activity, and the reduced baroreflex-SNA relationship during PEH, we determined whether: 1) RVLM neuronal activity is decreased during PEH, 2) GABA(A)-receptor… CONTINUE READING
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Role of the ventral medulla oblongata in blood pressure regulation

  • PG Guyenet
  • 1990
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