GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells.

@article{Resendes2006GAbindingPA,
  title={GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells.},
  author={Karen K. Resendes and Alan G. Rosmarin},
  journal={Molecular and cellular biology},
  year={2006},
  volume={26 8},
  pages={3060-70}
}
Expression of CD18, the beta chain of the leukocyte integrins, is transcriptionally regulated by retinoic acid (RA) in myeloid cells. Full RA responsiveness of the CD18 gene requires its proximal promoter, which lacks a retinoic acid response element (RARE). Rather, RA responsiveness of the CD18 proximal promoter requires ets sites that are bound by GA… CONTINUE READING