G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.

@article{Katoh2012G9aHM,
  title={G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.},
  author={Kimiko Katoh and Ryoji Yamazaki and Akishi Onishi and Rikako Sanuki and Takahisa Furukawa},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 49},
  pages={17658-70}
}
In vertebrate retinal development, various transcription factors are known to execute essential activities in gene regulation. Although epigenetic modification is considered to play a pivotal role in retinal development, the exact in vivo role of epigenetic regulation is still poorly understood. We observed that G9a histone methyltransferase, which… CONTINUE READING