G.N. Ramachandran

  title={G.N. Ramachandran},
  author={Easwara Subramanian},
  journal={Nature Structural Biology},
nature structural biology • volume 8 number 6 • june 2001 489 G.N. Ramachandran, an outstanding figure in the field of protein structure, passed away at the age of 78, on April 7, 2001, in Chennai (the erstwhile city of Madras), India. Ramachandran (G.N.R. or Ram to his friends and associates) was the founder of the ‘Madras school’ of conformational analysis of biopolymers. His discovery of the triple helical structure of collagen in 1955 and his analysis of the allowed conformations of… 
The Ramachandran Number: An Order Parameter for Protein Geometry
It is proposed that R might be used as an order parameter for protein geometry for a wide range of applications, and can be used to describe the geometric content of protein structures, and used to draw diagrams that reveal the frequency of occurrence of regular secondary structures and disordered regions in large protein datasets.
A closer look into the α-helix basin
Analysis of α-helical conformations acquired from the Protein Data Bank demonstrates that a conformational energy function of the α- helix backbone can be harmonically approximated on the (ρ, ϑ) space, which is not applicable to the (φ, ψ) space due to the diagonal distribution of the conformations.
The BackMAP Python module: how a simpler Ramachandran number can simplify the life of a protein simulator
The Ramachandran number (ℛ) is re-introduced as a residue-level structural metric that could simply the life of anyone contending with large numbers of protein backbone conformations (e.g., ensembles from NMR and trajectories from simulations).
Solution structure of a pentasaccharide representing the repeating unit of the O-antigen polysaccharide from Escherichia coli O142: NMR spectroscopy and molecular simulation studies.
NMR data are consistent with the presence of hydrogen bonding within the model of the repeating unit, and hydrogen-bond analysis of the trajectories from the molecular dynamics simulation revealed interresidue interactions to be important as a cluster of different hydrogen bonds and as a distinct highly populated hydrogen bond.
Collagen structure: new tricks from a very old dog.
  • J. Bella
  • Chemistry, Biology
    The Biochemical journal
  • 2016
The current understanding of the structure of the collagen triple helical domain (COL×3) is summarized and an overview of some of the new developments in collagen molecular engineering aiming to produce novel collagen-based materials with superior properties are given.
Bioinformatics—Structural Biology Interface
The field of bioinformatics has evolved such that the most pressing task now involves the analysis and interpretation of various types of data, including nucleotide and amino acid sequences, protein domains, and protein structures.
Missed opportunities in crystallography
This review analyzes missed opportunities of giants in the history of crystallography focusing on macromolecular crystallographers using Perutz, Pauling, Franklin as examples, although cases of particular historical, methodological or structural relevance are also described.
Stop Breast Cancer Now! Imagining Imaging Pathways Toward Search, Destroy, Cure, and Watchful Waiting of Premetastasis Breast Cancer
Tibor Tot has given me an unusual opportunity via his request to summarize my work in computed tomography (CT), which indeed since 1977 has been directed toward eliminating the scourge of breast
In vitro Sirius Red collagen assay measures the pattern shift from soluble to deposited collagen.
The results suggest that the newly synthesized soluble collagen can sensitively evaluate an agent's capacity for collagen production and Sirius Red is more useful than [(3)H]-proline because it is easier to use, more convenient, less time consuming, and does not require radioactive material.
Closure of skin incision by dual wavelength (980 and 1064 nm) laser application
It is concluded that 1 W, 5 J for 5 seconds CW mode laser application of 980 and 1064 nm combined beam form in skin incision closure was found to have absolute wound healing capability with minimal thermal alteration.


The Structure of Collagen
This paper applies helical diffraction theory to deduce the three-chain, coiled coil structure of collagen, a family of extracellular proteins that are a major component of connective tissue and make up one-third of all proteins in the human body.
Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution.
The structure of a protein triple helix has been determined by x-ray crystallographic studies of a collagen-like peptide containing a single substitution of the consensus sequence, which adopts a triple-helical structure that confirms the basic features determined from fiber diffraction studies on collagen.
Cataphoresis of Crystal Nuclei
RECENT observations on the crystallization of lithium sulphate by Helen Rae and A. E. Robinson may possibly provide a further example of the formation of crystallization nuclei bearing a net charge
The structure and action of proteins
Where you can find the the structure and action of proteins easily? Is it in the book store? On-line book store? are you sure? Keep in mind that you will find the book in this site. This book is very
Ramachandran – a biography
  • 1998