G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection.

@article{McCullough1997GTL,
  title={G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection.},
  author={April J. McCullough and S. M. Berget},
  journal={Molecular and cellular biology},
  year={1997},
  volume={17 8},
  pages={4562-71}
}
Splicing of small introns in lower eucaryotes can be distinguished from vertebrate splicing by the inability of such introns to be expanded and by the inability of splice site mutations to cause exon skipping-properties suggesting that the intron rather than the exon is the unit of recognition. Vertebrates do contain small introns. To see if they possess properties similar to small introns in lower eucaryotes, we studied the small second intron from the human alpha-globin gene. Mutation of the… CONTINUE READING

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