G-proteins in growth and apoptosis: lessons from the heart

@article{Adams2001GproteinsIG,
  title={G-proteins in growth and apoptosis: lessons from the heart},
  author={John W. Adams and Joan Brown},
  journal={Oncogene},
  year={2001},
  volume={20},
  pages={1626-1634}
}
The acute contractile function of the heart is controlled by the effects of released nonepinephrine (NE) on cardiac adrenergic receptors. NE can also act in a more chronic fashion to induce cardiomyocyte growth, characterized by cell enlargement (hypertrophy), increased protein synthesis, alterations in gene expression and addition of sarcomeres. These… CONTINUE READING