G proteins in development.

  title={G proteins in development.},
  author={Craig C. Malbon},
  journal={Nature reviews. Molecular cell biology},
  volume={6 9},
The focus of developmental biologists has expanded from the analysis of gene expression to include the analysis of cell signalling. Heterotrimeric G proteins (G proteins) mediate signalling from a superfamily of heptahelical receptors (G-protein-coupled receptors) to a smaller number of effector units that include adenylyl cyclases, phospholipase C and various ion channels. The convergence of developmental biology with cell signalling has now revealed overlaps in which G proteins mediate… CONTINUE READING


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