G proteins and pheromone signaling.

  title={G proteins and pheromone signaling.},
  author={Henrik G. Dohlman},
  journal={Annual review of physiology},
All cells have the capacity to respond to chemical and sensory stimuli. Central to many such signaling pathways is the heterotrimeric G protein, which transmits a signal from cell surface receptors to intracellular effectors. Recent studies using the yeast Saccharomyces cerevisiae have produced important advances in our understanding of G protein activation and inactivation. This review focuses on the mechanisms by which G proteins transmit a signal from peptide pheromone receptors to the… CONTINUE READING