G protein subunit Gγ13 is coexpressed with Gαo, Gβ3, and Gβ4 in retinal ON bipolar cells

@article{Huang2003GPS,
  title={G protein subunit G$\gamma$13 is coexpressed with G$\alpha$o, G$\beta$3, and G$\beta$4 in retinal ON bipolar cells},
  author={Liquan Huang and Marianna Max and Robert F. Margolskee and Hui Su and Richard H. Masland and Thomas Euler},
  journal={Journal of Comparative Neurology},
  year={2003},
  volume={455}
}
We investigated the expression of Gγ13, a recently discovered G protein subunit, and a selection of Gβ subunits in retinal bipolar cells, by using a transgenic mouse strain in which green fluorescent protein is strongly expressed in a single type of cone bipolar cell. The cells have ON morphology, and patch‐clamp recordings in slices confirmed that they are of the physiological ON type. Immunohistochemistry showed that Gγ13 is expressed in rod bipolar cells and ON cone bipolar cells, where it… 
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TLDR
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TLDR
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Electrical synapses in retinal ON cone bipolar cells: subtype-specific expression of connexins.
  • Yi HanS. Massey
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2005
TLDR
The results suggest that connexins are expressed in bipolar cells in a neuronal subtype-specific manner and that cx36/cx36 gap junctions form the heterologous electrical synapses between AII amacrine cells and BPGus-GFP cells.
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