G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective.

  title={G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective.},
  author={Anne Lafon and Kap-Hoon Han and J A Seo and J R Yu and Christophe d'Enfert},
  journal={Fungal genetics and biology : FG & B},
  volume={43 7},
We have carried out an in silico exploration of the genomes of Aspergillus nidulans, Aspergillus fumigatus, and Aspergillus oryzae, and identified components of G-protein/cAMP-mediated signaling. Putative G-protein coupled receptors (GPCRs) were distributed over nine classes. The GPCRs within classes were well conserved among aspergilli but varied in other ascomycetes. As previously observed in A. nidulans and other fungi, three Galpha, one Gbeta, and one Ggamma subunits of G proteins were… CONTINUE READING