G Protein beta subunit types differentially interact with a muscarinic receptor but not adenylyl cyclase type II or phospholipase C-beta 2/3.

@article{Hou2001GPB,
  title={G Protein beta subunit types differentially interact with a muscarinic receptor but not adenylyl cyclase type II or phospholipase C-beta 2/3.},
  author={Yongmin Hou and Vicky C-D Chang and Austin B Capper and Ronald Taussig and Narasimhan Gautam},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 23},
  pages={19982-8}
}
In comparison with the alpha subunit of G proteins, the role of the beta subunit in signaling is less well understood. During the regulation of effectors by the betagamma complex, it is known that the beta subunit contacts effectors directly, whereas the role of the beta subunit is undefined in receptor-G protein interaction. Among the five G protein beta subunits known, the beta(4) subunit type is the least studied. We compared the ability of betagamma complexes containing beta(4) and the well… CONTINUE READING