G Protein Pathways

@article{Neves2002GPP,
  title={G Protein Pathways},
  author={Susana R. Neves and Prahlad T. Ram and Ravi Iyengar},
  journal={Science},
  year={2002},
  volume={296},
  pages={1636 - 1639}
}
The heterotrimeric guanine nucleotide–binding proteins (G proteins) are signal transducers that communicate signals from many hormones, neurotransmitters, chemokines, and autocrine and paracrine factors. The extracellular signals are received by members of a large superfamily of receptors with seven membrane-spanning regions that activate the G proteins, which route the signals to several distinct intracellular signaling pathways. These pathways interact with one another to form a network that… 

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