G-Protein-Coupled Receptor Kinase 2 and Hypertension

@article{Santulli2013GProteinCoupledRK,
  title={G-Protein-Coupled Receptor Kinase 2 and Hypertension},
  author={Gaetano Santulli and Bruno Trimarco and Guido Iaccarino},
  journal={High Blood Pressure \& Cardiovascular Prevention},
  year={2013},
  volume={20},
  pages={5-12}
}
Numerous factors partake in the fine-tuning of arterial blood pressure. The heptahelical G-protein-coupled receptors (GPCRs) represent one of the largest classes of cell-surface receptors. Further, ligands directed at GPCRs account for nearly 30 % of current clinical pharmaceutical agents available. Given the wide variety of GPCRs involved in blood pressure control, it is reasonable to speculate for a potential role of established intermediaries involved in the GPCR desensitization process… Expand
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TLDR
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