G-CSF promotes autophagy and reduces neural tissue damage after spinal cord injury in mice

Abstract

Granulocyte colony-stimulating factor (G-CSF) was investigated for its capacity to induce autophagy and related neuroprotective mechanisms in an acute spinal cord injury model. To accomplish this goal, we established a mouse spinal cord hemisection model to test the effects of recombinant human G-CSF. The results showed that autophagy was activated after… (More)
DOI: 10.1038/labinvest.2015.120

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