G-CSF prevents the progression of atherosclerosis and neointimal formation in rabbits.

@article{Hasegawa2006GCSFPT,
  title={G-CSF prevents the progression of atherosclerosis and neointimal formation in rabbits.},
  author={Hiroshi Hasegawa and Hiroyuki Takano and Masashi Ohtsuka and Kazutaka Ueda and Yuriko Niitsuma and Yingjie Qin and Hiroyuki Tadokoro and Masashi Shiomi and Issei Komuro},
  journal={Biochemical and biophysical research communications},
  year={2006},
  volume={344 1},
  pages={370-6}
}
Granulocyte colony-stimulating factor (G-CSF) prevents left ventricular remodeling after myocardial infarction, but its effect on atherosclerosis is unknown. We examined two kinds of rabbit atherosclerosis models. Myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHL-MI) rabbits were treated with G-CSF or saline for 7 days from 14 months old. The vascular injury models were created by inflating angioplasty balloon in the iliac artery of rabbits and were divided into G-CSF and… CONTINUE READING